CTICasesExtraosseous Multiple Myeloma
Imaging findings
CT chest and abdomen in a patient with multiple myeloma show multiple soft tissue masses in the anterior mediastinum, right hilum, pleura, and chest wall, along with multiple low-attenuation liver lesions. Biopsy confirmed extraosseous plasmacytoma metastases.
Key takeaways
While multiple myeloma typically involves the skeletal system, extraosseous or extramedullary plasmacytomas can occur in advanced disease. They manifest as infiltrative, soft tissue masses seeding the mediastinum, pleura, chest wall, and visceral organs, and carry a poor prognosis.
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