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Metastatic Small Cell Lung Cancer with Mosaic Attenuation

Metastatic Small Cell Lung Cancer with Mosaic Attenuation▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Mosaic attenuation in the lungs with relatively small vessels in areas of low attenuation, indicative of obstructive small airways disease. A few very small nodules were present. Enlarged mediastinal lymph nodes were noted, but there was no dominant mass in the chest.

Key takeaways

This was a very unusual case of metastatic small cell neuroendocrine carcinoma presenting without a typical primary mass. The mosaic attenuation and small nodules initially raised suspicion for DIPNECH. However, the diagnosis of small cell cancer was confirmed by biopsy of neck and mediastinal lymph nodes. This case highlights a rare presentation of small cell cancer and its potential association with patterns resembling small airways disease.

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