CTICasesSystemic mastocytosis with pulmonary involvement
Imaging findings
Thin-section chest CT demonstrates a combination of diffuse reticulation, ground-glass opacities, centrilobular nodules, and tiny cystic spaces throughout the lungs. Osseous structures show osteosclerosis of the spine.
Key takeaways
Systemic mastocytosis is a clonal hematologic disorder that can rarely involve the pulmonary parenchyma, presenting radiographically with reticulation, ground-glass changes, centrilobular nodules, and small cysts due to mast cell infiltration and associated fibrosis.
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