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Extranodal Rosai-Dorfman disease

Imaging findings

Chest CT shows a large fibroinflammatory soft tissue mass encasing the ascending aorta, pulmonary trunk, and pericardium, with extension along the right internal mammary vessels into the chest wall, without significant coronary artery compression.

Key takeaways

Extranodal Rosai-Dorfman disease is a rare histiocytic proliferative disorder that can present as a large mediastinal and pericardial mass, mimicking lymphoma or sclerosing mediastinitis. Complete surgical excision or biopsy is required to demonstrate typical histopathological features.

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