Pleural mesothelioma
Imaging findings
Chest CT shows atypical, nodular, and lobulated pleural thickening involving the mediastinal pleural surfaces and major fissures, associated with a persistent pleural effusion. Thoracoscopy with biopsy confirmed malignant pleural mesothelioma.
Key takeaways
Pleural mesothelioma can present early or atypically with nodular pleural thickening confined to the mediastinal pleura or fissures, rather than a diffuse pleural rind. Suspicious nodular pleural thickening on CT in a patient with unexplained pleural effusion warrants thoracoscopic biopsy.
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