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High-grade pleomorphic spindle cell sarcoma of the chest wall

Imaging findings

Chest and abdominal CT show a large, aggressive mass in the right lower chest wall causing destruction of the adjacent rib, traversing the diaphragm, and extending into the subphrenic space.

Key takeaways

High-grade pleomorphic spindle cell sarcomas of the chest wall are aggressive, destructive neoplasms. They can grow to large sizes, causing direct bone destruction and traversing anatomical boundaries such as the diaphragm into the abdomen.

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