CTICasesAcute Fibrinous Organizing Pneumonia
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Imaging findings
Chest X-ray showed vague reticular nodular patterns and nodules scattered throughout both lungs. CT scans revealed numerous tiny, diffuse "miliary-type" nodules scattered throughout both lungs, some slightly larger ground-glass nodules, areas of ground-glass consolidation, and subpleural consolidation. Airways were not thick-walled. A similar case presented with centrilobular nodules, described as small pellets of organizing pneumonia in the small bronchioles.
Key takeaways
Acute fibrinous organizing pneumonia (AFOP) is a rare condition that can present with tiny nodules (sometimes miliary-like or centrilobular) or diffuse alveolar damage. It can also appear as areas of ground-glass opacity or consolidation. Pathologically, it is thought to be a continuum of organizing pneumonia with a predominant fibrinous component. AFOP can be idiopathic, and its imaging findings may resemble atypical pneumonias or diffuse organizing pneumonia. Diagnosis often requires biopsy. Some cases have a poor prognosis.
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