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Cryptogenic Organizing Pneumonia

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Imaging findings

Serial chest radiographs and CT scans show multifocal, asymmetric, peribronchial areas of ground-glass opacity and consolidation that progressed over a week despite antibiotic therapy. Follow-up imaging shows rapid clearance and improvement after the initiation of steroid therapy.

Key takeaways

Cryptogenic organizing pneumonia (COP) is a form of idiopathic interstitial pneumonia characterized by patchy, multifocal consolidations that typically mimic community-acquired pneumonia but fail to respond to antibiotics. A dramatic response to corticosteroid therapy is a classic diagnostic feature.

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