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Cardiac Sarcoidosis Mimicking Arrhythmogenic Right Ventricular Dysplasia (ARVD)

Imaging findings

Cardiac MRI shows an enlarged right ventricle compared to the left, with motion abnormalities including dyskinesis and bulging (almost aneurysms) of the RV wall and interventricular septum. Late gadolinium enhancement (LGE) is positive in portions of the RV, especially along the septum and outflow tract, and also in the inferolateral wall of the left ventricle. Endomyocardial biopsy confirmed sarcoidosis.

Key takeaways

Cardiac sarcoidosis can closely mimic arrhythmogenic right ventricular dysplasia (ARVD) on MRI, presenting with right ventricular enlargement, dyskinesis, and late gadolinium enhancement. The presence of LV involvement, while possible in ARVD, may also raise suspicion for sarcoidosis. Biopsy is often necessary for definitive diagnosis due to the overlapping imaging features.

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