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Post-infarction ventricular septal defect

Imaging findings

Gated cardiac CT demonstrates a focal defect (rupture) measuring approximately one centimeter in the inferior aspect of the interventricular septum, in a patient with a recent myocardial infarction and right ventricular dilation.

Key takeaways

Ventricular septal rupture is a well-known, high-mortality mechanical complication of acute myocardial infarction, typically occurring 3 to 5 days post-infarction. Gated cardiac CT plays an important role in surgical or percutaneous closure planning.

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