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Strongyloides Hyperinfection Syndrome

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Imaging findings

A patient with a history of renal transplant developed widespread pulmonary opacities within five days of a normal chest radiograph. CT imaging demonstrates numerous discreet nodules, indicative of a hematogenous miliary pattern, with probable superimposed diffuse alveolar damage.

Key takeaways

Strongyloides hyperinfection syndrome can manifest as a rapid and severe pulmonary process in immunocompromised patients, such as those with organ transplants. The rapid progression to widespread miliary nodules and diffuse alveolar damage reflects massive dissemination of larvae through the bloodstream. Early recognition is critical for timely treatment.

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