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Fibrotic Organizing Pneumonia

Fibrotic Organizing Pneumonia▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

High-resolution CT of a patient with systemic lupus erythematosus shows patchy ground-glass opacities combined with a classic perilobular pattern, characterized by arcade-like airspace opacities along the borders of the secondary pulmonary lobules. Follow-up imaging after three months of steroid therapy demonstrates significant resolution of the active cellular infiltration with some residual fine peripheral articulation and fibrosis.

Key takeaways

Perilobular opacities are highly characteristic of organizing pneumonia and represent airspace inflammation tracking along the periphery of the secondary pulmonary lobules. In the context of connective tissue disease such as lupus, organizing pneumonia can have a fibrotic component that responds partially to steroid therapy, leaving behind residual linear scars.

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