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Dendriform Pulmonary Ossification

Imaging findings

CT chest shows bilateral lower-lobe-predominant, branching calcified opacities following the bronchovascular bundles, in the setting of chronic fibrotic lung disease (NSIP pattern) secondary to scleroderma.

Key takeaways

Dendriform pulmonary ossification (DPO) is a rare form of heterotopic bone formation in the lung parenchyma. It presents as branching, calcified spicules resembling a tree branching pattern, strongly associated with chronic lung injury, gastroesophageal reflux/aspiration, and fibrotic ILD.

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