Dendriform Pulmonary Ossification
Imaging findings
CT chest shows bilateral lower-lobe-predominant, branching calcified opacities following the bronchovascular bundles, in the setting of chronic fibrotic lung disease (NSIP pattern) secondary to scleroderma.
Key takeaways
Dendriform pulmonary ossification (DPO) is a rare form of heterotopic bone formation in the lung parenchyma. It presents as branching, calcified spicules resembling a tree branching pattern, strongly associated with chronic lung injury, gastroesophageal reflux/aspiration, and fibrotic ILD.
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