Acute graft-versus-host disease
Imaging findings
Chest CT in an allogeneic stem cell transplant recipient shows a symmetric organizing pneumonia pattern with peribronchial consolidations, ground-glass opacities, and arcade-like subpleural bands, in the absence of active infection.
Key takeaways
While chronic graft-versus-host disease typically presents as bronchiolitis obliterans (air trapping), acute lung graft-versus-host disease can manifest as a sterile organizing pneumonia pattern. It must be differentiated from pulmonary infection and drug toxicity.
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