CTICasesRadiation recall pneumonitis
Imaging findings
Serial chest radiographs and CT scans show progressive, migrating, peripheral consolidations and ground-glass opacities with an organizing pneumonia pattern (reverse halo sign) that originated in a prior spine radiation field and subsequently spread after administration of paclitaxel.
Key takeaways
Radiation recall pneumonitis is an inflammatory lung reaction where chemotherapy triggers a severe inflammatory response in previously irradiated lung. The combination of chemotherapy and prior radiation can prime the lung, leading to organizing pneumonia that can migrate outside the initial radiation field.
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