CTICasesAML Lymphatic Blast Infiltration
Imaging findings
Chest CT demonstrates prominent peribronchial cuffing, septal lines, and subpleural interstitial thickening resembling severe pulmonary edema or lymphangitic carcinomatosis. Bone marrow biopsy confirmed acute myeloid leukemia (AML).
Key takeaways
Acute myeloid leukemia can manifest in the lungs as leukemic cell infiltration of the pulmonary lymphatics. This mimics interstitial edema or lymphangitic carcinomatosis on CT and can be a sign of early disease progression.
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