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Transthyretin cardiac amyloidosis (ATTR amyloidosis) on bone scan

Imaging findings

Technetium bone scan shows intense, diffuse myocardial radiotracer uptake (greater than bone). Biopsy confirmed ATTR amyloidosis.

Key takeaways

Bone-seeking radiotracers (such as Technetium-99m pyrophosphate or oxidronate) accumulate in the myocardium of patients with ATTR amyloidosis. This non-invasive test is highly specific for differentiating ATTR from AL amyloidosis.

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