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Cardiac Amyloidosis

Imaging findings

Cardiac MRI shows ventricular wall thickening and extensive late gadolinium enhancement. The myocardium fails to null on inversion recovery sequences. Chest CT shows pleural effusions and nodular thickening along the interlobular septa and subpleural space.

Key takeaways

Cardiac amyloidosis classically presents with ventricular thickening, diffuse late gadolinium enhancement, and failure to null the myocardium on MRI. Associated pulmonary involvement (alveolar septal amyloidosis) can mimic interstitial lung disease or edema.

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