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Pulmonary Follicular Lymphoma in Evans Syndrome

Imaging findings

Chest CT in a woman in her 40s/50s with history of Evans syndrome demonstrates multiple bilateral, airway-centric, peribronchial nodules with mixed solid and ground-glass components, some demonstrating early cavitation. Biopsy of a nodule confirms follicular lymphoma.

Key takeaways

Evans syndrome is a rare autoimmune disorder characterized by the simultaneous or sequential development of autoimmune hemolytic anemia and immune thrombocytopenic purpura. It is associated with an increased risk of lymphoproliferative disorders. Pulmonary follicular lymphoma can present as multiple peribronchial nodules, resembling mucosa-associated lymphoid tissue (MALT) lymphoma or follicular bronchiolitis, and requires long-term follow-up.

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