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Ganglioneuroma

Imaging findings

Chest CT shows a vertically elongated, well-defined mass in the left posterior paraspinal region of the posterior mediastinum, mimicking a paraspinal hematoma post motor vehicle accident. The mass exhibits homogeneous low attenuation (30-40 Hounsfield units) and contains surrounding vascularity. Histopathological analysis post surgical resection confirms a ganglioneuroma.

Key takeaways

Ganglioneuromas are benign, slow-growing neurogenic tumors of sympathetic origin (arising from sympathetic ganglion cells). They characteristically present in the posterior mediastinum as vertically oriented, paraspinal masses that can remodeled adjacent bony structures. On CT, they frequently exhibit low attenuation due to a high content of myxoid matrix and adipose tissue, which can be misdiagnosed as fluid collections, cysts, or hematomas in a trauma setting.

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