CTICasesIdiopathic Pulmonary Fibrosis (Probable UIP Pattern)
Imaging findings
High-resolution chest CT shows peripheral reticulation and traction bronchiectasis involving the upper and lower lung zones in a diffuse distribution, without evidence of subpleural honeycombing. According to the Fleischner Society consensus guidelines, this appearance represents a 'probable UIP' pattern of disease.
Key takeaways
The diagnosis of usual interstitial pneumonia (UIP) on HRCT has been refined by guidelines (such as the Fleischner Society white paper). A 'probable UIP' pattern is defined by reticulation and traction bronchiectasis in a subpleural, basal-predominant distribution without honeycombing. In the appropriate clinical setting (e.g., age and exclusion of secondary causes), a probable UIP pattern on CT is highly specific for idiopathic pulmonary fibrosis (IPF) and can obviate the need for a surgical lung biopsy.
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