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NUT Midline Carcinoma

Imaging findings

Chest radiograph and CT show a large, aggressive left lung and hilar mass with associated hilar lymphadenopathy. Pathological analysis confirmed NUT midline carcinoma.

Key takeaways

NUT midline carcinoma is an extremely aggressive, poorly differentiated squamous cell carcinoma defined by rearrangement of the NUT gene. It typically affects young patients and carries a very poor prognosis.

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