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Epipericardial Fat Necrosis

Epipericardial Fat Necrosis▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

CT reveals a funny attenuation lesion with a surrounding ring of soft tissue attenuation in the anterior mediastinum, indenting the left lung parenchyma. This was initially thought to be a fat-containing anterior mediastinal tumor.

Key takeaways

Epipericardial fat necrosis is a benign inflammatory condition that can mimic a mediastinal tumor. It typically presents as a fat-containing lesion with a surrounding rim of inflammation. While often associated with pleural effusions, it may also present without one. Biopsy is typically definitive for diagnosis.

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