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Incidentally Discovered Small Thymoma

Imaging findings

In a patient under CT surveillance for a history of colon cancer, a small, well-circumscribed mediastinal opacity with smooth margins is identified, off-center from the typical anterior mediastinal location, and shows slow interval enlargement between two studies several months apart with no other findings to suggest metastatic disease.

Key takeaways

A solitary, slowly enlarging, well-circumscribed mediastinal nodule in a cancer-surveillance patient -- without other findings of metastatic disease -- should raise suspicion for an incidental thymoma rather than metastasis; resection confirmed a typical small thymoma, an increasingly recognized incidental finding on screening and surveillance CT.

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