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Plexiform Neurofibromatosis

Imaging findings

Extensive, bulky soft tissue masses involving the mediastinum, paraspinal regions, axillae, and neck, consistent with plexiform neurofibromas. The case highlighted involvement of the phrenic nerve.

Key takeaways

Plexiform neurofibromatosis can be diffuse and infiltrative. Careful mapping of nerves, such as the phrenic nerve, is important in these patients.

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