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Fitz-Hugh-Curtis Syndrome

Imaging findings

CT of the chest and upper abdomen in a 21-year-old female presenting with right-sided pleuritic chest pain shows normal pulmonary arteries. However, there is a small amount of fluid and perihepatic soft-tissue hyperemia surrounding the liver capsule. Pelvic inflammatory disease workup confirms chlamydia infection, consistent with Fitz-Hugh-Curtis syndrome (perihepatitis).

Key takeaways

Fitz-Hugh-Curtis syndrome is a complication of pelvic inflammatory disease characterized by inflammation of the liver capsule (perihepatitis), typically caused by Chlamydia trachomatis or Neisseria gonorrhoeae. It classically presents as acute right upper quadrant or pleuritic chest pain that can mimic pulmonary embolism, pneumonia, or cholecystitis. CT is diagnostic, showing transient subcapsular hepatic enhancement/hyperemia.

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