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Nodular Lymphoid Hyperplasia

Imaging findings

CT chest shows multiple, irregular, bizarre-looking pulmonary nodules, some of which are cavitated or contain small internal cystic spaces, distributed predominantly in the lower lobes. The nodules progressed slowly over eight years.

Key takeaways

Nodular lymphoid hyperplasia (NLH) is a rare, benign, reactive lymphoproliferative disease of the lung. It typically presents with slowly progressive lower-lobe nodules or masses that can cavitate. While benign, it is frequently clonal and must be differentiated pathologically from MALT lymphoma.

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