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Pulmonary Cryptococcosis

Imaging findings

CT chest in a heart transplant recipient shows a left pleural effusion and a solitary nodule in the left upper lobe with a low-attenuation center. Serology was positive for Cryptococcus antigen.

Key takeaways

Cryptococcosis is a common opportunistic fungal infection in transplant recipients, typically presenting as a solitary or multiple pulmonary nodules that can cavitate or demonstrate low-attenuation centers. Cryptococcal antigen serology is highly specific, but cannot distinguish between Cryptococcus neoformans and Cryptococcus gattii.

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