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Congenital Pulmonary Airway Malformation (CPAM) Mimicking Adenocarcinoma

Congenital Pulmonary Airway Malformation (CPAM) Mimicking Adenocarcinoma▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

A cystic lesion in the left lower lobe is seen, described as bubbly with some respiratory motion on low-resolution imaging. PET showed no metabolic activity, but the morphology was concerning for adenocarcinoma in the absence of large soft tissue components suggesting invasion.

Key takeaways

This case illustrates the limitations of PET imaging, as the lack of metabolic activity did not rule out malignancy. Despite the PET findings, the lesion's morphology prompted a left lower lobectomy. Pathology revealed a congenital pulmonary adenomatoid malformation (CPAM/CCAM). While good news for the patient, it highlights the diagnostic challenge and the extent of intervention sometimes required for benign lesions mimicking cancer.

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