CTICasesLibman-Sacks Endocarditis
Imaging findings
Cardiac MRI and echocardiography in a female patient with systemic lupus erythematosus (SLE) show multiple large, irregular, sterile vegetations on the mitral valve, with severe mitral regurgitation. Brain MRI shows multiple acute, small, punctate subcortical infarcts in the occipital, frontal, and parietal regions on diffusion-weighted imaging, representing systemic embolization.
Key takeaways
Libman-Sacks endocarditis is a form of non-bacterial verrucous endocarditis characterized by sterile vegetations on the cardiac valves (most commonly the mitral and aortic valves) in patients with SLE or antiphospholipid syndrome. These vegetations are prone to embolization, causing embolic strokes or systemic ischemia, and can lead to severe valvular dysfunction requiring surgical valve replacement.
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