CTICasesHigh-Grade B-Cell Lymphoma with Cardiac Involvement
Imaging findings
Chest and abdominal CT scans show extensive, infiltrating, necrotic soft-tissue masses in the lower neck, supraclavicular fossae, axillae, and mesenteric fat. In addition, there is a prominent interatrial septal mass indenting the left atrium. Cardiac MRI confirms the presence of an enhancing, infiltrative tissue mass involving the interatrial septum and extending along the inferior vena cava and right atrium.
Key takeaways
High-grade triple-hit B-cell lymphomas are highly aggressive tumors that can present with widespread extra-nodal involvement. The interatrial septum is a classic, underrecognized site of secondary cardiac involvement in leukemia and lymphoma, and cardiac MRI is useful for characterizing the extent and tissue characteristics of the tumor.
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