CTICasesSystemic Sclerosis with Soft Tissue Calcinosis and NSIP
Imaging findings
Frontal chest radiograph reveals extensive, dense, tumor-like calcifications clustered symmetrically around both shoulder joints and tracking down into the proximal arm musculature. High-resolution chest CT shows classic features of systemic sclerosis-associated interstitial lung disease, including bilateral basilar-predominant reticulation and traction bronchiectasis characteristic of a fibrosing nonspecific interstitial pneumonia pattern, alongside the extensive periarticular calcinosis.
Key takeaways
Severe calcinosis cutis and periarticular soft-tissue calcification are classic manifestations of systemic sclerosis, particularly in the limited cutaneous subtype. The presence of extensive soft-tissue calcification combined with a basilar-predominant fibrosing nonspecific interstitial pneumonia pattern is highly specific for scleroderma.
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