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Acute Interstitial Pneumonia (Hamman-Rich Syndrome)

Imaging findings

Sequential CT scans and radiographs demonstrate rapidly progressive, diffuse, geographic ground-glass opacities, dense consolidations, and early traction bronchiectasis, culminating in the development of pneumomediastinum within weeks.

Key takeaways

Acute interstitial pneumonia, also known as Hamman-Rich syndrome, is a rapidly progressive and highly lethal form of idiopathic diffuse alveolar damage. It presents with acute respiratory failure mimicking ARDS without an identifiable trigger, and early imaging findings of ground-glass opacity can rapidly evolve into severe architectural distortion and traction bronchiectasis.

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