CTICasesHypoxic pulmonary vasoconstriction and mosaic perfusion
Imaging findings
CT scan demonstrates intraluminal mucus material in the proximal airways of the lower lobes, right greater than left, with associated regional decrease in lung attenuation and small vessel size (mosaic perfusion) and slow flow in the right inferior pulmonary vein.
Key takeaways
Airway obstruction from mucus plugging leads to alveolar hypoxia and subsequent hypoxic pulmonary vasoconstriction, which causes decreased regional blood flow (mosaic perfusion) visible on CT.
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