CTICasesDedifferentiated Anterior Mediastinal Liposarcoma
Imaging findings
Serial chest CT examinations demonstrate a large, progressively growing anterior mediastinal mass with mixed fat and soft-tissue attenuation, associated with a right-sided pleural effusion. Over time, the mass shows an increase in the size and ratio of solid, soft-tissue components relative to the fatty components.
Key takeaways
Primary mediastinal liposarcoma is a rare mesenchymal tumor that can grow to a massive size. The presence of discrete, progressive nodular or mass-like soft-tissue areas within a lipomatous tumor represents dedifferentiated components, which are highly malignant and dictate the prognosis and necessity for surgical resection.
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