CTICasesSecondary Cardiac Lymphoma in a Patient with Sarcoidosis (Sarcoidosis-Lymphoma Syndrome)
Imaging findings
Contrast-enhanced chest CT demonstrates a moderate pericardial effusion and an infiltrative, poorly enhancing soft-tissue mass in the right atrioventricular groove. The mass wraps around the inferior surface of the heart, extends into the interventricular septum, and is accompanied by mediastinal lymphadenopathy.
Key takeaways
Cardiac lymphoma is an infiltrative neoplastic process that typically grows along the tissue planes and anatomical scaffolding of the heart, such as the atrioventricular groove and septum, which helps differentiate it from angiosarcoma. The concurrence of sarcoidosis and lymphoma is a known clinical association termed "sarcoidosis-lymphoma syndrome," where patients with sarcoidosis carry an increased risk of developing lymphoproliferative disorders.
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