CTICasesLangerhans Cell Histiocytosis
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Imaging findings
Well-defined ground glass nodular densities, some ill-defined solid nodules, and some showing cavitation were observed, with more "Cheerios" appearing in the lower lungs and similar abnormalities in the left costophrenic angle. This atypical pattern for adrenal carcinoma metastases prompted consideration of an inflammatory spectrum.
Key takeaways
Langerhans cell histiocytosis (LCH) can present with cavitary nodules ('Cheerios'), particularly in young, smoking patients. While LCH is typically upper lobe predominant, these inflammatory nodules can extend to costophrenic angles, challenging conventional teaching. The cystic form of LCH is becoming less commonly observed, possibly due to earlier diagnosis and treatment.
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