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Esophageal Large Cell Neuroendocrine Carcinoma

Esophageal Large Cell Neuroendocrine Carcinoma▶ Watch on YouTube — age-restricted, cannot embed here

Imaging findings

Radiograph shows a filling defect at the esophagogastric junction. Ultrasound-guided biopsy (FNA) initially suggested melanoma, but core biopsy later diagnosed large cell neuroendocrine carcinoma. Endoscopy confirmed a mass at the esophagogastric junction.

Key takeaways

Esophageal masses, even if subtle on radiograph, require further evaluation. Large cell neuroendocrine carcinoma of the esophagus is rare. Discrepancies between FNA and core biopsy can occur, necessitating full surgical pathology for definitive diagnosis.

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