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Subcarinal High-Grade Sarcoma

Imaging findings

Serial chest radiographs show progressive widening and increased density of the subcarinal space over one year. CT chest shows a large, infiltrative subcarinal mass splaying the main bronchi and directly eroding into an adjacent thoracic vertebral body.

Key takeaways

Slowly progressive widening of the mediastinum or subcarinal space on radiographs warrants cross-sectional imaging to exclude neoplasm. High-grade sarcomas of the mediastinum are aggressive, infiltrative tumors that can cause local bone destruction (vertebral invasion) and bronchial compression.

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