CTICasesExtramedullary Hematopoiesis and Group 5 Pulmonary Hypertension
Imaging findings
Chest CT shows posterior paraspinal/mediastinal masses (extramedullary hematopoiesis), diffuse marrow expansion of the ribs, and a dilated pulmonary artery. The patient had beta thalassemia and a history of splenectomy.
Key takeaways
Pulmonary hypertension in beta thalassemia can be multifactorial and is classified as Group 5. Splenectomy is a recognized risk factor that accelerates the development of pulmonary hypertension in these patients.
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