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Rheumatoid Arthritis Associated Advanced Cystic Fibrotic Lung Disease

Imaging findings

Chest CT in a 55-year-old male smoker with rheumatoid arthritis shows advanced fibrotic lung disease with prominent cystic spaces, basal predominance, and relative subpleural sparing. The traction bronchiectasis is out of proportion to typical UIP, and severe emphysema is coexistent.

Key takeaways

Connective tissue disease-associated ILD can present with complex, atypical fibrotic patterns combining emphysema, traction bronchiectasis, and atypical cystic spaces. Distinguishing these from idiopathic pulmonary fibrosis is clinically important, often aided by serologic panels.

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