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Löffler Endomyocarditis

Imaging findings

Chest CT demonstrates a pericardial effusion and a non-enhancing right ventricular apical filling defect. Cardiac MRI confirms endocardial necrosis and thrombosis with apical obliteration of the right ventricle, and characteristic hyperenhancement surrounding the thrombus on delayed imaging, in the setting of marked peripheral blood eosinophilia.

Key takeaways

Löffler endomyocarditis (eosinophilic myocarditis) is a rare manifestation of hypereosinophilic syndrome. It evolves through three stages: acute necrosis, thrombosis with apical obliteration (which can mimic an endocardial mass or thickening on CT), and late restrictive cardiomyopathy.

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