Chronic Beryllium Disease
Imaging findings
Chest radiographs and CT scans spanning over 20 years show stable, non-calcified, bilateral hilar and mediastinal lymphadenopathy without lung parenchymal abnormalities.
Key takeaways
Chronic beryllium disease (CBD) should be considered in patients with occupational exposure (such as nuclear cleanup) who present with persistent mediastinal and hilar lymphadenopathy mimicking sarcoidosis. Beryllium lymphocyte proliferation testing can be negative in a subset of patients, especially those without lung parenchymal involvement.
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