Chondromyxoid Fibroma of the Rib
Imaging findings
Chest radiograph and CT show an expansile, well-circumscribed right rib lesion containing a matrix mix of fat, calcium, and soft tissue, with cortical thinning but no aggressive periosteal reaction. Resection specimen confirms a lobulated cartilaginous mass.
Key takeaways
Chondromyxoid fibroma is a rare, benign primary cartilaginous bone tumor. When arising from the rib or chest wall, it can mimic malignant primary tumors like chondrosarcoma, requiring histopathological confirmation for diagnosis.
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