CTICasesWilliams-Campbell Syndrome
Imaging findings
High-resolution CT shows dilated, thin-walled, branching 4th-to-6th order airways with a corrugated appearance of the trachea/central airways, sparing the central and extreme peripheral bronchi. Expiratory CT demonstrates hypercollapsibility of the central airways, indicating excessive dynamic airway collapse (EDAC) / tracheobronchomalacia.
Key takeaways
Williams-Campbell syndrome is a structural airway disorder characterized by congenital cartilage deficiency in 4th-to-6th order bronchi, leading to bronchiectasis. It can present later in life (e.g., in elderly patients) and frequently manifests with dynamic airway collapse or tracheobronchomalacia.
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