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Thymolipoma

Imaging findings

Case one shows a massive, bulky, predominantly fatty mass in the left hemithorax on chest radiography. CT imaging shows a large anterior mediastinal mass composed of mature adipose tissue mixed with soft tissue elements, hanging down from the thymus. Case two shows a smaller fat-containing lesion in the right cardiophrenic angle with feeding vessels extending down from the thymic region, which remained stable for over ten years.

Key takeaways

Thymolipomas are rare, benign, slow-growing anterior mediastinal tumors composed of mature adipose tissue and elements of normal thymic tissue. Although they can grow to a massive size and drape into the lower chest or cardiophrenic angles, their connection to the thymus and characteristic fat content on CT allow for a confident non-invasive diagnosis.

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