CTICasesNodular Pulmonary Amyloidosis
Imaging findings
Serial chest radiographs spanning 20 years show slowly progressive, multiple bilateral pulmonary nodules, predominantly in the lung bases, which develop dense calcified centers over time. Chest CT from 2017 confirms multiple calcifying and ossifying pulmonary amyloidomas accompanied by calcified mediastinal and hilar lymphadenopathy.
Key takeaways
Nodular pulmonary amyloidosis (pulmonary amyloidomas) typically presents as slowly growing, calcifying, or ossifying lung nodules, often in the lower lobes, which can progress over decades without systemic plasma cell dyscrasia. The presence of calcification in both the parenchymal nodules and associated lymph nodes is a characteristic feature of this benign deposition disease.
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