CTICasesFamilial Pulmonary Fibrosis with TERT Mutation
Imaging findings
Serial CT scans over five years show progressive atypical fibrotic lung disease characterized by basilar and central reticular and ground-glass changes, confirmed to be familial pulmonary fibrosis from a TERT mutation.
Key takeaways
TERT telomerase mutations are associated with familial pulmonary fibrosis. The CT pattern is often atypical, presenting with a fibrotic NSIP or indeterminate pattern (with central disease) rather than typical UIP, but usually progress to UIP histologically.
AI-assisted summary — may contain errors. Verify against the source video. Learn more
More from this webinar
- Breast Radiation-Associated Organizing PneumoniaIatrogenic
- Scleroderma-Associated UIP with Exuberant HoneycombingILD
- ProtectDuo Right Ventricular Assist DeviceIatrogenic
- Intercostal Artery Laceration with Active BleedingTrauma
- Retained Jugular Needle Fragments from IV Drug AbuseInfection
- Extruded Vertebroplasty Cement in the Azygos VeinIatrogenic
- Posterior Mediastinal GanglioneuromaNeoplastic
- Cardiac Bronchus with Accessory LobeCongenital
See all cases from July 30, 2020 →