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Squamous Cell Carcinoma of the Parotid Gland with Pulmonary Metastases in a Heart Transplant Recipient

Imaging findings

A heart transplant recipient developed a skin lesion on the neck, which was squamous cell carcinoma of the parotid gland spreading to the overlying skin and was confirmed after a large resection. Follow-up CT shows several peripheral, basal-predominant pulmonary nodules typical of metastases. The patient then deteriorated, and later radiographs show multiple non-healing fractures. The recording ends as these images are being shown.

Key takeaways

Solid organ transplant recipients have a much higher risk of aggressive squamous cell carcinoma, which can involve the parotid gland and skin. New peripheral, lower-lobe-predominant nodules in such a patient are typical of hematogenous metastases. Multiple non-healing fractures in a deteriorating patient should prompt a search for skeletal metastases.

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