CTICasesHIV Lipodystrophy
Imaging findings
Chest radiographs and CT images demonstrate a prominent mass-like area of soft tissue on the anterior chest wall. CT scan shows extensive infiltration and thickening of the subcutaneous fat along the anterior chest wall bilaterally, with interspersed glandular breast tissue, representing classic features of lipodystrophy.
Key takeaways
HIV-associated lipodystrophy is a disorder of fat distribution commonly associated with older antiretroviral therapies. It can present as abnormal fat accumulation in the chest wall, neck, or abdomen, mimicking a soft tissue tumor, silicone injection, or gynecomastia, and can be confirmed by biopsy showing benign adipose tissue with dystrophic changes.
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